The BBSRC Facility for Spatially Resolved Single and Sub-cellular "omics"

BBSRC Seismic Facility for Spatially Resolved Single and Sub-cellular "omics"

Selected Publications


  1. Spatial single cell metabolomics: Current challenges and future developments, Kyle D.G.Saunders, Holly-May Lewis, Dany J.V.Beste, Olivier Cexus, Melanie J.Bailey, Current Opinion in Chemical Biology, 75, 102327, 2023
  2. Single-Cell Lipidomics Using Analytical Flow LC-MS Characterizes the Response to Chemotherapy in Cultured Pancreatic Cancer Cells, Kyle D.G.Saunders, Johanna von Gerichten, Holly-May Lewis, Priyanka Gupta, Matt Spick, Catia Costa, Eirini Velliou, Melanie J.Bailey, Analytical Chemistry, 95(39), 14727–14735, 2023
  3. Expanding the boundaries of atomic spectroscopy at the single-cell level: critical review of SP-ICP-MS, LIBS and LA-ICP-MS advances for the elemental analysis of tissues and single cells, Claire Davison, Dany Beste, Melanie Bailey, Mónica Felipe-Sotelo, Analytical and Bioanalytical Chemistry, 415, 6931–6950, 2023
  4. Nanocapillary sampling coupled to liquid chromatography mass spectrometry delivers single cell drug measurement and lipid fingerprints, Holly-May Lewis, Priyanka Gupta, Kyle D.G.Saunders, Shazneil Briones, Johanna von Gerichten, Paul A.Townsend, Eirini Vellious, Dany J.V.Beste, Olivier Cexus, Roger Webb, Melanie J.Bailey, Analyst, 148, 1041-1049, 2023
  5. Single-Cell Untargeted Lipidomics Using Liquid Chromatography and Data-Dependent Acquisition after Live Cell Selection, Johanna von Gerichten, Kyle D. G. Saunders, Anastasia Kontiza, Carla F. Newman, George Mayson, Dany J. V. Beste, Eirini Velliou, Anthony D. Whetton, Melanie J. Bailey, Anal. Chem., 96(18), 6922–6929, 2024
  6. Single-Cell Lipidomics: An Automated and Accessible Microfluidic Workflow Validated by Capillary Sampling, Anastasia Kontiza, Johanna von Gerichten, Kyle D. G. Saunders, Matt Spick, Anthony D. Whetton, Carla F. Newman, Melanie J. Bailey, Anal. Chem., 0003-2700, 2024
  7. Single cell–inductively coupled plasma–mass spectrometry (SC-ICP-MS) reveals metallic heterogeneity in a macrophage model of infectious diseases, Claire Davison, Jordan Pascoe, Melanie Bailey, Dany J. V. Beste & Mónica Felipe-Sotelo, Analytical and Bioanalytical Chemistry,2024


In The News


  1. BBC News Article
  2. Single Cell Lipidomics May Unlock New Cancer Treatments
  3. Yokogawa News Brief

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